Anne Zehnacker-Rentien


Anne Zehnacker-Rentien




Directeur de recherche CNRS (DR1)
Head of « Centre Laser de l’Université Paris Sud (CLUPS)
Head of the team “Structure et dynamique des systèmes complexes isolés photoexcités (SYSIPHE)” of the ISMO Institute.
Member of the advisory Editorial Board of Phys Chem. Chem. Phys since 2008
Member of the advisory Editorial Board of Journal of Molecular Structure since 2016
Member of the driving committee of the excellence cluster PALM “Physique, Atomes, Lumière, Matière”


  • My team focuses on laser spectroscopy, photophysics, and photochemistry of organic molecules in the gas phase. We aim at describing at the molecular level the forces responsible for molecular recognition, in particular for chiral recognition. We also study the influence of stereochemistry on the spectroscopy and the photostability of life-related molecules. To this end, the group combines laser spectroscopy, supersonic expansions or ion traps with theoretical chemistry calculations and vibrational circular dichroism in solution and in the solid phase.



Ph-D / lecturer Université Paris VI


Chargé de recherche “CNRS Laboratoire de Photophysique Moléculaire/Orsay


Post doc ” chargé de recherche ” CNRS in DRECAM/SPAM CEN Saclay.Theoretical Chemistry group


“Directeur de recherche ” CNRS (DR2)


“Directeur de recherche ” CNRS (DR1)


CNRS Bronze Medal for young investigators


Awards of the Physical Chemistry section of the French Chemical Society


” Honorary Wilsmore Fellow” of Melbourne University


Honorary member of the French Chemical Society


Chirality recognition between neutral molecules in the gas phase Zehnacker, A.; Suhm, M. A. Angewandte Chemie-International Edition 47, 6970, (2008) (invited review article)


The role of weak hydrogen bonds in chiral recognition D. Scuderi, K. Le Barbu-Debus, A. Zehnacker Phys. Chem. Chem. Phys. 13, 17916 (2011) (invited perspective article)


Chirality effects in gas-phase spectroscopy and photophysics of molecular and ionic complexes: contribution of low and room temperature studies. A. Zehnacker. Int Reviews in Physical Chemistry 33, 151-207, (2014) (Invited review)

Structural Characterization of the UV-Induced Fragmentation Products in an Ion Trap by Infrared Multiple Photon Dissociation Spectroscopy. Scuderi D, Lepere V, Piani G, Bouchet A, Zehnacker-Rentien A. Journal of Physical Chemistry Letters 5, 56, (2014)

Unraveling non-covalent interactions within flexible biomolecules: from electron density topology to gas phase spectroscopy R Chaudret, B De Courcy, J Contreras-Garcia, E Gloaguen, A Zehnacker-Rentien, M Mons, J-P Piquemal Physical Chemistry Chemical Physics 16 , 9876-9891 (2014)


Spectroscopic Study of Jet-Cooled Deuterated Porphycenes: Unusual Isotopic Effects on Proton Tunneling ET Mengesha, A Zehnacker-Rentien, J Sepioł, M Kijak, J Waluk The Journal of Physical Chemistry B 119, 2193–2203 (2015)


Vibrational circular dichroism of a 2,5-diketopiperazine (DKP) peptide: Evidence for dimer formation in cyclo LL or LD diphenylalanine in the solid state. Perez-Mellor, A.; Zehnacker, A. Chirality, 29 (2), 89-96. (2017)


Molecular Recognition by a Short Partial Peptide of the Adrenergic Receptor: A Bottom-Up Approach.Sekiguchi, T.; Tamura, M.; Oba, H.; Çarçarbal, P.; Lozada-Garcia, R. R.; Zehnacker-Rentien, A.; Grégoire, G.; Ishiuchi, S.-i.; Fujii, M. Angewandte Chemie International Edition, 10.1002/anie.201712976 (2018)

Effect of Puckering Motion and Hydrogen Bond Formation on the Vibrational Circular Dichroism Spectrum of a Flexible Molecule: The Case of (S)-1-Indanol. Physical Chemistry Chemical Physics Le Barbu-Debus, K.; Scherrer, A.; Bouchet, A.; Sebastiani, D.; Vuilleumier, R.; Zehnacker, A.: PCCP 20 (21), 14635-14646 (2018)

Stereochemistry-dependent Hydrogen Bonds Stabilise Stacked Conformations in Jet-Cooled Cyclic Dipeptides: (LD) vs. (LL) cyclo Tyrosine Tyrosine Feriel Ben Nasr, Ariel Pérez-Mellor), Ivan Alata), Valeria Lepere, Nejm-Eddine Jaïdane, Anne Zehnacker Faraday Discussions (2018)


Can the Partial Peptide SIVSF of b2-Adrenergic Receptor Recognize Chirality of Epinephrine Neurotransmitter? Tamura, M.; Sekiguchi, T.; Ishiuchi, S.-I.; Zehnacker-Rentien, A.; Fujii, M., The Journal of Physical Chemistry Letters 2019.

Conformational Study of the Jet-Cooled Diketopiperazine Peptide cyclo Tyrosyl-Prolyl. Perez-Mellor, A.; Alata, I.; Lepere, V.; Zehnacker, A., The Journal of Physical Chemistry. B 2019, 123 (28), 6023-6033.

Vibrational Circular Dichroism as a Probe of Solid-State Organisation of Derivatives of Cyclic b-Amino Acids: cis– and trans-2-aminocyclobutane-1-carboxylic acid. Declerck, V.; Perez-Mellor, A.; Guillot, R.; Aitken, D. J.; Mons, M.; Zehnacker, A., Chirality 2019, 31 (8), 547-560.

Effects of Complexation with Sulfuric Acid on the Photodissociation of Protonated Cinchona Alkaloids in the Gas Phase. Ben Nasr, F.; Alata, I.; Scuderi, D.; Lepere, V.; Brenner, V.; Jaidane, N.-E.; Zehnacker, A., Physical Chemistry Chemical Physics 2019, 21 (28), 15439-15451.