Jinhua Dong

細胞生物学研究

Jinhua Dong

特任教授

遺伝子工学蛋白質工学抗体工学免疫測定

研究プロジェクト

  • 提示技術による新型抗体の開発及び応用

  • Open Sandwich免疫測定法及びQuenchbody免疫蛍光プローブの研究

2007-2009

東京大学大学院工学系研究科リサーチフェロー

2009-2011

日本学術振興会外国人特別研究員(東京大学)

2011-2013

静岡大学創造科学技術大学院研究員、特任助教

2013-2016

東京工業大学 資源化学研究所 助教

2016-2017

臨沂大学化学化工学院 教授

2017-

東京工業大学科学技術創成研究院 特任教授
Weifang Medical University, School of Bioscience and Technology Professor

2017

Excellent Paper Award of The Society for Biotechnology, Japan

2015

フジサンケイビジネスアイ第29回独創性を拓く先端技術大賞特別賞

2020

Dong, J., Miyake, C., Yasuda, T., Oyama, H., Morita, I., Tsukahara, T., Takahashi, M., Jeong, H.J., Kitaguchi, T., Kobayashi, N., and Ueda, H., PM Q-probe: a fluorescent binding protein that converts many antibodies to a fluorescent biosensor, Biosens. Bioelectron, 165,112425, 2020

Dong, J., Oka, Y., Jeong, H.J., Ohmuro-Matsuyama, Y., and Ueda, H., Detection and destruction of HER2-positive cancer cells by Ultra Quenchbody-siRNA complex, Biotechnol. Bioeng., 117, 1259-1269, 2020

2019

Cong, Y., Dong, H., Wei, X., Zhang, L., Bai, J., Wu, J., Huang, X.J., Gao, Z., Ueda, H. and Dong, J., A novel murine antibody and an Open sandwich immunoassay for the detection of clenbuterol, Ecotoxicol. Environ. Saf., 182,109473, 2019

Gong, Z., Liu, X., Dong, J., Zhang, W., Jiang, Y., Zhang, J., Feng, W., Chen, K., Bai, J., Transition from vesicles to nanofibres in the enzymatic self-assemblies of an amphiphilic peptide as an antitumour drug carrier, Nanoscale, 11(33):15479-15486, 2019

2018

Dong, J., Fujita, R., Zako, T., Ueda, H., Construction of Quenchbodies to detect and image Amyloid β oligomers, Anal. Biochem., 550,61-67, 2018

Zhao, S., Dong, J., Jeong, H.J., Okumura, K., Ueda, H., Rapid detection of the neonicotinoid insecticide imidacloprid using a quenchbody assay, Anal. Bioanal. Chem., 410(17),4219-4226, 2018

Su, J., Dong, J., Kitaguchi, T., Ohmuro-Matsuyama, Y., Ueda, H., Noncompetitive homogeneous immunodetection of small molecules based on β-glucuronidase complementation, Analyst, 143, 2096-2101, 2018

2017

Dong, J., Shichiri, M., Chung, C.I., Shibata, T., Uchida, K., Hagihara, Y., Yoshida, Y., Ueda, H., An Open Sandwich immunoassay for detection of 13(R,S)-Hydroxy-9(E),11(E)-octadecadienoic acid, Analyst, 142(5), 787-793, 2017

Dong, J., Ueda, H., ELISA-type assays of trace biomarkers using microfluidic methods, WIREs Nanomed. Nanobiotechnol., e1457, 2017

Wongso, D., Dong, J., Ueda, H., Kitaguchi, T., Flashbody: a next generation Fluobody with fluorescence intensity enhanced by antigen binding, Anal. Chem., 89(12),6719-6725, 2017

Jeong, H.J., Kawamura, T., Iida, M., Kawahigashi, Y., Takigawa, M., Ohmuro-Matsuyama, M., Chung, C.I., Dong, J., Kondoh, M., Ueda, H., Development of a Quenchbody for the detection and imaging of the cancer-related tight-junction-associated membrane protein claudin, Anal Chem., 89(20),10783-10789, 2017

2016

Dong, J., Jeong, H.J., Ueda, H., Preparation of Quenchbodies by protein transamination reaction, J. Biosci. Bioeng., 122(1), 125-130, 2016

2015

Dong, J., Kojima, T., Ohashi H., Ueda, H., Optimal fusion of antibody binding domains resulted in higher affinity and wider specificity, J. Biosci. Bioeng., 120(5),504-9, 2015

Chung, C.I., Makino, R., Dong, J., Ueda, H., Open flower fluoroimmunoassay: a general method to make fluorescent protein-based immunosensor probes, Anal. Chem., 87(6), 3513-9, 2015

2014

Dong, J., Otsuki, T., Kato, T., Park, E.Y., Tracking Neospora caninum parasites using chimera monoclonal antibodies against its surface antigen-related sequences (rNcSRS2), J. Biosci. Bioeng., 117(3), 351-357, 2014

2013

Zhou, H.*, Dong, J.*, Deo, V.K., Park, E.Y., Lee, J. Detection of anti-Neospora antibodies in bovine serum by using spiky Au-CdTe nanocomplexes, Sens. actuators. B Chem., 178,192-199 (2013) *equal contributions

Dong, J., Sakurai, A., Nomura, N., Park, E.Y., Shibasaki, F., Ueda, H., Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus, PloS One, 8(4), e61158, 2013

2012

Dong, J., Otsuki, T., Kato, T., Park, E.Y., Development of a diagnostic method for neosporosis in cattle using recombinant Neospora caninum proteins, BMC Biotechnol., 12,19, 2012

2011

Islam, K., Ihara, M., Dong, J., Kasagi, N., Mori, T., Ueda, H., Direct construction of open-sandwich enzyme immunoassay for one-step noncompetitive detection of thyroid hormone T4, Anal. Chem., 83(3),1008-1014, 2011

2009

Dong, J., Ihara, M., Ueda, H., Antibody Fab display system that can perform open-sandwich ELISA, Anal. Biochem., 386(1),36-44, 2009

2007

Dong, J., Tamaru, Araki, T., Molecular cloning, expression, and characterization of a β-agarase gene, agaD, from a marine bacterium, Vibrio sp. strain PO-303, Biosci. Biotechnol. Biochem., 71(1),38-46, 2007

Dong, J., Tamaru, Y., Araki, T., A unique β-agarase, AgaA, from a marine bacterium, Vibrio sp. strain PO-303, Appl. Microbiol. Biot., 74(6),1248-1255, 2007

2006

Dong, J., Hashikawa, S., Konishi, T., Tamaru, Y., Araki, T., Cloning of the novel gene encoding β-Agarase C from a marine bacterium, Vibrio sp. strain PO-303, and characterization of the gene product, Appl. Environ. Microbiol., 72(9),6399-6410, 2006