Hisakazu Mihara

Cell Biology

Hisakazu Mihara

Professor

Chemical BiologyPeptide Engineering

Biography

Hisakazu Mihara received his Doctor of Science degree in chemistry from Kyushu University under the direction of N. Izumiya in 1986. He was a postdoctoral fellow in E. T. Kaiser’s group at the Rockefeller University, New York (1986-1988). He was appointed as an assistant professor in applied chemistry at Kyushu Institute of Technology in 1988 and was promoted to an associate professor in applied chemistry at Nagasaki University in 1993 and in bioengineering at Tokyo Institute of Technology in 1995. He was a professor in Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology (2005-2015). Currently, he is a professor and dean of School of Life Science and Technology, Tokyo Institute of Technology (2016-2020). His research interests include peptide design and synthesis, de novo design of functional peptides including self-assembling peptides for biomaterials and peptide biochips, and peptide-phage display technology for drug design and peptide probes.

Expectations for WRHI

Expanding the research hub in life sciences

2016-2020

Dean,  School of Life Science and Technology,  Tokyo Institute of Technology

2016-

Professor,  School of Life Science and Technology,  Tokyo Institute of Technology

2015-2016

Dean,  Graduate School of Bioscience and Biotechnology,  Tokyo Institute of Technology

2005-2016

Professor,  Graduate School of Bioscience and Biotechnology,  Tokyo Institute of Technology

1995-2005

Associate Professor,  Graduate School of Bioscience and Biotechnology,  Tokyo Institute of Technology

1993-1995

Associate Professor,  Nagasaki University

1988-1993

Assistant Professor,  Kyushu Institute of Technology

1986-1988

Postdoctoral Fellow,  The Rockefeller University

2015

Chemical Society of Japan Award for Creative Work

2011

Award for Good Education, Tokyo Tech

2009

Award of Japan Bioindustry Association

2005

Fellow of The Royal Society of Chemistry (FRSC)

2001

Teshima Memorial Award for Research

2019

Fukunaga, H. Tsutsumi, H. Mihara, Self-Assembling Peptides as Building Blocks of Functional Materials for Biomedical Applications,  Bull. Chem. Soc. Jpn., 92, 391-399 (2019)

2018

Syahir, K. Kajikawa, H. Mihara, Signal Enhancement Strategies for Refractive Index-Sensitive Nanobiosensor,   Protein Peptide Lett., 25, 34-41 (2018) 

2017

I.V. Chang, H.Tsutsumi, H. Mihara, Screening for Concanavalin A Binders from a Mannose-modified alpha-Helix Peptide Phage Library,   Mol. BioSyst., 13, 2222-2225 (2017)

2016

K. Fukunaga, H. Tsutsumi, H. Mihara, Cell Differentiation on Disk- and String-Shaped Hydrogels Fabricated From Ca2+-Responsive Self-Assembling Peptides,  Biopolymers, 106, 476-483 (2016) 

2015

H. Tsutsumi, K. Nakano, H. Mihara, Dihydrofolate Reductase Inhibitory Peptides Screened from a Structured Designed beta-Loop Peptide Library Displayed on Phage,  Mol. BioSyst., 11, 2713-2716 (2015)

2014

H.J. Park, H. Tsutsumi, H. Mihara, Cell-selective Intracellular Drug Delivery Using Doxorubicin and alpha-Helical Peptides Conjugated to Gold Nanoparticles,  Biomaterials, 35, 3480-3487 (2014)