Anne Zehnacker-Rentien

1986-1988  Ph-D / lecturer Université Paris VI
1988-2003  “Research associate” CNRS
2003-2016  “Research director” CNRS (DR2)
2005-         Head of the team “Interactions moléculaires:
                  structure et dynamique” of the ISMO Institute
2012-         Head of ” Centre Laser de l’Université Paris Sud “
2016-         “Research director” CNRS (DR1)
2018-       Specially Appointed Professor. Clean Environment
                  Unit, IIR, Tokyo Tech

Field of Specialization
Laser Spectroscopy / Photophysics / Photo-Induced Processes

Clean Environment Unit (IIR, Tokyo Tech)
Paris-Sud University(France)

Research Hub Group:Materials and Devices international hub group

Research Highlights

  • My team focuses on laser spectroscopy, photophysics, and photochemistry of organic molecules in the gas phase. We aim at describing at the molecular level the forces responsible for molecular recognition, in particular for chiral recognition. We also study the influence of stereochemistry on the spectroscopy and the photostability of life-related molecules. To this end, the group combines laser spectroscopy, supersonic expansions or ion traps with theoretical chemistry calculations and vibrational circular dichroism in solution and in the solid phase.


Selected Awards 

  • 1992 : CNRS Bronze Medal for young investigators
  • 2003 : Awards of the Physical Chemistry section of the French Chemical Society
  • 2016 : “Honorary Wilsmore Fellow” of Melbourne University
  • 2017: Honorary member of the French Chemical Society

Selected Publications 


  • Chirality recognition between neutral molecules in the gas phase Zehnacker, A.; Suhm, M. A. Angewandte Chemie-International Edition 47, 6970, (2008) (invited review article)
  • The role of weak hydrogen bonds in chiral recognition D. Scuderi, K. Le Barbu-Debus, A. Zehnacker Phys. Chem. Chem. Phys. 13, 17916 (2011) (invited perspective article)
  • Chirality effects in gas-phase spectroscopy and photophysics of molecular and ionic complexes: contribution of low and room temperature studies. A. Zehnacker. Int Reviews in Physical Chemistry 33, 151-207, (2014) (Invited review)
  • Structural Characterization of the UV-Induced Fragmentation Products in an Ion Trap by Infrared Multiple Photon Dissociation Spectroscopy. Scuderi D, Lepere V, Piani G, Bouchet A, Zehnacker-Rentien A. Journal of Physical Chemistry Letters 5, 56, (2014)
  • Unraveling non-covalent interactions within flexible biomolecules: from electron density topology to gas phase spectroscopy R Chaudret, B De Courcy, J Contreras-Garcia, E Gloaguen, A Zehnacker-Rentien, M Mons, J-P Piquemal Physical Chemistry Chemical Physics 16 , 9876-9891 (2014)
  • Spectroscopic Study of Jet-Cooled Deuterated Porphycenes: Unusual Isotopic Effects on Proton Tunneling ET Mengesha, A Zehnacker-Rentien, J Sepioł, M Kijak, J Waluk The Journal of Physical Chemistry B 119, 2193–2203 (2015)
  • Vibrational circular dichroism of a 2,5-diketopiperazine (DKP) peptide: Evidence for dimer formation in cyclo LL or LD diphenylalanine in the solid state. Perez-Mellor, A.; Zehnacker, A. Chirality, 29 (2), 89-96. (2017)
  • Molecular Recognition by a Short Partial Peptide of the Adrenergic Receptor: A Bottom-Up Approach.Sekiguchi, T.; Tamura, M.; Oba, H.; Çarçarbal, P.; Lozada-Garcia, R. R.; Zehnacker-Rentien, A.; Grégoire, G.; Ishiuchi, S.-i.; Fujii, M. Angewandte Chemie International Edition, 10.1002/anie.201712976 (2018)
  • Effect of Puckering Motion and Hydrogen Bond Formation on the Vibrational Circular Dichroism Spectrum of a Flexible Molecule: The Case of (S)-1-Indanol. Physical Chemistry Chemical Physics Le Barbu-Debus, K.; Scherrer, A.; Bouchet, A.; Sebastiani, D.; Vuilleumier, R.; Zehnacker, A.: PCCP 20 (21), 14635-14646 (2018)
  • Stereochemistry-dependent Hydrogen Bonds Stabilise Stacked Conformations in Jet-Cooled Cyclic Dipeptides: (LD) vs. (LL) cyclo Tyrosine Tyrosine Feriel Ben Nasr, Ariel Pérez-Mellor), Ivan Alata), Valeria Lepere, Nejm-Eddine Jaïdane, Anne Zehnacker Faraday Discussions (2018)