Frederic Leroux

1998–2001: Lausanne大: 助教授, 
2001– 2003: Lausanne大: 准教授, 
2003–2009: Strasbourg大: CNRS 准研究員, 
2005: Strasbourg大: ハビリタチオン
2009-: Strasbourg大: CNRS 研究所長,
2014-: Bayer- CNRS 有機フッ素化学研究所長
2018- 東京工業大学物質理工学院特任教授


物質理工学院(SMCT, Tokyo Tech)
University of Strasbourg(フランス)

グループ名 :細胞生物学研究国際ハブグループ


  • トリフルオロメトキシ複素環を初めて合成した。
  • P-キラルなフォスホールを初めて合成した。
  • アレンの反応に基づいて光学的に純粋なビアリルを合成し不斉触媒化学へ適用。


  • 2017: CNRS Innovation;
  • 2014: Savoir(s): “Une chimie innovante autour du fluor Savoir(s)”;
  • 2014: DNA: “Le Fluor pour moteur”;
  • 2014: CNRS Innovation.


  • 2002 JSP fellowship, Bürgenstock Stereochemistry conference, Bürgenstock Lucerne, CH.

  • 2008 Fellow of the Royal Society of Chemistry (FRSC).

  • 2013 Bayer lecturer; 2014 Wiley-Schlosser lecturer.

  • 2014 Wiley-Schlosser lecturer.

  • 2016 Bayer publication award.


  • Schmitt, S. Bouvet, B. Pegot, A. Panossian, J. P. Vors, S. Pazenok, E. Magnier, F. R. Leroux,, Fluoroalkyl Amino Reagents for the Introduction of the Fluoro(trifluoromethoxy)methyl Group onto Arenes and Heterocycles. Org. Lett. 2017, 19, pp. 4960-4963.
  • Schmitt, A. Panossian, J. P. Vors, C. Funke, N. Lui, S. Pazenok, F. R. Leroux, A Major Advance in the Synthesis of Fluoroalkyl Pyrazoles: Tuneable Regioselectivity and Broad Substitution Patterns. Chem. Eur. J. 2016, 22, pp. 11239-11244.
  • Schmitt, B. Rugeri, A. Panossian, J.-P. Vors, S. Pazenok, F. R. Leroux, In Situ Generated Fluorinated Iminium Salts for Difluoromethylation and Difluoroacetylation., Org. Lett. 2015, 17, pp. 4510-4513.
  • R. Leroux, A. Berthelot, L. Bonnafoux, A. Panossian, Transition‐Metal‐Free Atropo‐Selective Synthesis of Biaryl Compounds Based on Arynes. Chem. Eur. J. 2012, 18, pp. 14232-14236.
  • Bonnafoux, R. Gramage-Doria, F. Colobert, F. R. Leroux, Catalytic Palladium Phosphination: Modular Synthesis of C-1-Symmetric Biaryl-Based Diphosphines. Chem. Eur. J. 2011, 17, pp. 11008-11016