Ana Pombo

プロフィール
2000–2002 英国MRC Clinical Sciences Centre (CSC)
グループリーダー
2002–2013 英国MRC-CSC プログラムリーダー
2002–2007 英国Imperial College London (ICL)
Honorary上級講師
2007–2011 英国ICL Honorary准教授
2011–2012 英国ICL Honorary教授
2012–2015 英国ICL 教授
2013– 独国Berlin Institute for Medical Systems Biology, Max Delbruck Centre for Molecular Medicine, Berlin-Buch グループリーダー
2013– 独国Humboldt University, Berlin 教授

専門分野
ゲノム構造 / 遺伝子制御 / クロマチン構造

Humboldt University, Berlin(ドイツ)

 https://pombolab.wordpress.com/
ana.pombo@mdc-berlin.de

グループ名:細胞生物学研究国際ハブグループ

研究ハイライト

  • 細胞核内のゲノム構造と遺伝子制御

主な受賞歴

  • 2007
    Robert Feulgen Prize 2007, Society for Histochemistry
  • 1998 – 2002
    Royal Society Dorothy Hodgkin Fellowship, University of Oxford and MRC Clinical Sciences Centre, London, UK.
  • 1997 – 2000
    Hayward Junior Research Fellowship, Oriel College, Oxford, UK.

主な論文

  • Beagrie RA, Scialdone A, Schueler M, Kraemer DC, Chotalia M, Xie SQ, Barbieri M, de Santiago I, Lavitas LM, Branco MR, Fraser J, Dostie J, Game L, Dillon N, Edwards PA, Nicodemi M, Pombo A. Complex multi-enhancer contacts captured by genome architecture mapping. Nature. 2017 Mar 23;543(7646):519-524.
  • Beagrie RA, Pombo A. Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription. Bioessays. 2016 Sep;38(9):881-93.
  • Fraser J, Ferrai C, Chiariello AM, Schueler M, Rito T, Laudanno G, Barbieri M, Moore BL, Kraemer DC, Aitken S, Xie SQ, Morris KJ, Itoh M, Kawaji H, Jaeger I, Hayashizaki Y, Carninci P, Forrest AR; FANTOM Consortium., Semple CA, Dostie J, Pombo A, Nicodemi M. Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation. Mol Syst Biol. 2015 Dec 23;11(12):852.
  • Dias JD, Rito T, Torlai Triglia E, Kukalev A, Ferrai C, Chotalia M, Brookes E, Kimura H, Pombo A. Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells. Elife. 2015 Dec 19;4. pii: e11215.
  • Pombo A, Dillon N. Three-dimensional genome architecture: players and mechanisms. Nat Rev Mol Cell Biol. 2015 Apr;16(4):245-57.