Yoshinori Ohsumi

Profile
1977-1986 Research Associate, Department of Biology, Faculty of Science, The University of Tokyo
1986-1988 Lecturer, Department of Biology, Faculty of Science, The University of Tokyo
1988-1996 Associate Professor, Department of Biology, College of Arts and Sciences, The University of Tokyo
1996-2004 Professor, Department of Cell Biology, National Institute for Basic Biology
2004-2009 Professor, Department of Cell Biology, National Institute for Basic Biology 
2009-2016 Specially Appointed Professor, Advanced Research Organization, Integrated Research Institute, Tokyo Institute of Technology 
2016-  Distinguished Specially Appointed Professor, Institute of Innovative Research, Tokyo Institute ofTechnology
2014-  Honorary Professor, Tokyo Institute of Technology

Field of Specialization
Proteolysis / Biological membrane / Cell structure・function /Autophagy

Cell Biology Center(IIR, Tokyo Tech)

 http://www.ohsumilab.aro.iri.titech.ac.jp/english.html

Research Hub Group :Cutting-edge Cell Biology international hub group

Research Highlights

  • Since our discovery of autophagy in yeast 28 years ago, the primary objective of our research group has been the molecular characterization of autophagy. Through the pioneering use of genetics in our studies, we were able to turn the field of autophagy on its head and trigger an explosion in autophagy research that continues apace.

Press

  • November, 2016 
    Professor Ohsumi receives 2016 Order of Culture
  • December, 2016 
    Professor Ohsumi wins 2017 Breakthrough Prize In Life Sciences
  • December, 2016 
    The Nobel Prize in Physiology or Medicine 2016 was awarded to Professor Ohsumi and Professor Ohsumi gives Nobel Lecture in Stockholm

Selected Awards

  • 2005 
    Fujiwara Award
  • 2009 
    Asahi Prize
  • 2012 
    Kyoto Prize
  • 2013 
    Thomson Reuters Citation Laureates
  • 2015 
    Canada Gairdner International Award
  • 2016 
    Order of Culture
  • 2016 
    Breakthrough Prize in Life Sciences
  • 2016 
    The Nobel Prize in Physiology or Medicine

Recent Publications

  • Recycling of iron via autophagy is critical for the transition from glycolytic to respiratory growth. Horie T, Kawamata T, Matsunami M, Ohsumi Y. J. Biol. Chem., 2017, 10.1074/jbc.M116.762963, [Faculty of 1000], in press
  • Zinc starvation induces autophagy in yeast. Kawamata T, Horie T, Matsunami M, Sasaki M, Ohsumi Y J. Biol. Chem., 2017, 10.1074/jbc.M116.762948, [editor’s pick up], in press
  • The intrinsically disordered protein Atg13 mediates supramolecular assembly of autophagy initiation complexes. Yamamoto H, Fujioka Y, Suzuki SW, Noshiro D, Suzuki H, Kondo-Kakuta C, Kimura Y, Hirano H, Ando T, Noda NN & Ohsumi Y Dev. Cell., 10.1016/j.devcel.2016.06.015
  • Structural basis for receptor-mediated selective autophagy of aminopeptidase I aggregates. Yamasaki A, Watanabe Y, Adachi W, Suzuki K, Matoba K, Kirisako H, Kumeta H, Nakatogawa H, Ohsumi Y, Inagaki F, Noda NN* Cell Rep. 2016, 16, 19-27