Toru HISABORI

Profile
1982 Master of Science, Waseda University
1985 Doctor of Science, Waseda University
1985 Assist. Prof. at Waseda Univ.
1987 Assist. Prof. at Yokohama City Univ.
1995 Assoc. Prof. at CRL, Tokyo Tech.
2009 Professor at CRL, Tokyo Tech.
2012 Vice Director, CRL, Tokyo Tech.
2016 Professor, IIR, Tokyo Tech.

Field of Specialization
Plant Biochemistry, Bioenergetics

Laboratory for Chemistry and Life Science(IIR, Tokyo Tech)

http://www.res.titech.ac.jp/~junkan/Hisabori_HomePageE/index.html
 thisabor@res.titech.ac.jp

Research Hub Group :Cutting-edge Cell Biology international hub group

Research Highlights

  • Molecular mechanism of the redox regulation of the chloroplast-type ATP synthase

  • Comprehensive analysis of the target enzymes of the redox mediator thioredoxin

Press

  • June 2016:We revealed the novel redox regulation pathway in plant chloroplast via NTRC, the hybrid protein of thioredoxin reductase and thioredoxin (Proc. Natl. Acad. Sci. USA 2016)

  •  Dec 2015:We reported the metabolic engineering of cyanobacteria Anabaena sp. PCC7120 to produce ammonia (Plant Cell Physiol. 2015)

Selected Awards 

  • Yamada Science Foundation (4/1996)

  • Tejima Research Paper Award (2/2017)

Selected Publications

  • 1986年 山田科学振興財団研究助成
  • 2017年 手島精一記念研究論文賞

主な論文

  • Murakami S, Kondo K, Katayama S, Hara S, Sunamura EI, Yamashita E, Groth G, Hisabori T. “Structure of the γ-ε complex of cyanobacterial F1-ATPase reveals a suppression mechanism of the γ subunit on ATP-hydrolysis in phototrophs.” Biochem J. 2018 Jul 27. pii: BCJ20180481 (2018).

  • Yoshida K, Hisabori T. “Distinct electron transfer from ferredoxin-thioredoxin reductase to multiple thioredoxin isoforms in chloroplasts” Biochem J. 474(8):1347-1360 (2017).

  • Yoshida K, Hisabori T. “Two distinct redox cascades cooperatively regulate chloroplast functions and sustain plant viability”Proc Natl Acad Sci U S A. 113(27):E3967-3976 (2016).

  • Sunamura E-I, et al. “A conformational change of the  subunit indirectly regulates the activity of cyanobacterial F1-ATPase”J. Biol. Chem. 287(46):38695-38704 (2012).

  • Groth G., Hisabori, T., Lill, H., Bald, D. “Substitution of a single amino acid switches the tentoxin resistant thermophilic F1-ATPase into a tentoxin sensitive enzyme”J. Biol. Chem. 277, 20117-20119 (2002)