Jim E. Haber

Profile
972-1977 Assistant Professor, Brandeis University
1977-1984 Associate Professor, Brandeis University
1984- Professor, Brandeis University
2017- Specially Appointed Professor, Tokyo Institute of Technology

Field of Specialization
Chromosome dynamics / homologous recombination / DNA double strand break repair

Cell Biology Center(IIR, Tokyo Tech)
Brandeis University(U.S.A)

 http://www.bio.brandeis.edu/haberlab/index.html
 haber@brandeis.edu

Research Hub Group :Cutting-edge Cell Biology international hub group

Research Highlights

  • Our lab studies how potentially lethal breaks in the DNA double helix are repaired and what effects they have on the cell.

Selected Awards

  • 1996
    Fellow, American Academy of Microbiology
  • 2005
    Fellow, American Association for the Advancement of Science
  • 2007
    NIH MERIT award
  • 2008
    Fellow, Radcliffe Institute of Advanced Study
  • 2009
    Member, American Academy of Arts and Sciences
  • 2010
    Member, National Academy of Sciences
  • 2011
    Thomas Hunt Morgan Medal for Lifetime Achievement in Genetics, Genetics Society of America

Selected Publications

  • New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe. Takahisa Maki, Naoto Ogura, James E Haber, Hiroshi Iwasaki, Genevieve Thon. PLoS Genet. (2018) 14(5):e1007424.
  • Anand R, Beach A, Li K and Haber JE (2017) Rad51-mediated double-strand break repair and mismatch correction of divergent substrates. Nature 544, 377–380
  • Tsabar M, Waterman DP, Aguilar F, Katsnelson L, Eapen VV, Memisoglu G, Haber JE. (2016). Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair. Genes Dev. 30, 1211-24.
  • Lee CS, Lee K, Legube G and Haber JE. (2014) Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break. Nat Struct Mol Biol. 21, 103-109.
  • Tsaponina O and Haber JE. (2014) Frequent Interchromosomal Template Switches during Gene Conversion in S. cerevisiae. Mol Cell 55, 615-625.
  • Hicks WM, Kim M and Haber JE. (2010) Increased mutagenesis and unique mutation signature associated with mitotic gene conversion. Science 329, 82-85.
  • Lydeard JR, Jain S, Yamaguchi M and Haber JE. (2007). Break-induced replication and telomerase-independent telomere maintenance require Pol32. Nature 448, 820-823.
  • Ira G, Malkova, A, Liberi G, Foiani M, and Haber JE. (2003) Srs2 and Sgs1-Top3 Suppress Crossovers during Double-Strand Break Repair in Yeast. Cell 115, 401-411.
  • Valencia MM, Bentele MB, Vaze MG, Herrmann E, Kraus, Lee SE, Schar P and Haber JE. (2001) NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature 414, 666-9.