中村 浩之

Profile
1995-1997 Assistant Prof., Basic Research Center of Organic Chemistry, Kyushu Univ.
1997-2002 Assistant Prof., Graduate School of Science ., Tohoku Univ.
2002-2006 Assoc. Prof., Dep. Chem., Gakushuin Univ.
2006-2013 Professor, Dep. Chem., Gakushuin Univ.
2013-2016 Professor, CRL, Tokyo Institute of Technology
2016- Professor, IIR, Tokyo Institute of Technology

Field of Specialization
Organic Chemistry / Chemical Biology/ Medicinal Chemistry

Laboratory for Chemistry and Life Science (IIR, Tokyo Tech)

 http://syn.res.titech.ac.jp/en/
 hiro@res.titech.ac.jp

Research Hub Group:Cutting-edge Cell Biology international hub group

Research Highlights 

  • Selective Purification and Chemical Labeling of Target Protein(April, 2017)
  • Site-Selective Multifunctionalization of Isoxazoles(August, 2016)
  • Efficient Neutron Capture Therapy using closo-Dodecaborate Albumin Conjugates(August, 2016)

Press

  • Dec. 2016
    “Exploring the Exciting and Forbidden Worlds of the Benzophenone Photophore” was published in the American Chemical Society Journal “Chemical Review”.
  • Nov. 2016
    “Total Synthesis of Feglymycin” published in Nature Communications was introduced into news papers, Nikkei Sangyo Shinbun and Kagaku Shinbun.
  • Aug. 2018
    “Maleimide-Functionalized closo-Dodecaborate Albumin Conjugates” published in Journal of Controlled Release wasintroduced into a news paper, Nikkei Sangyo Shinbun

Selected Awards

  • 1999: The Award of the Chemical Society of Japan for Young Chemists
  • 2007: The Incentive Award of the Japanese Society for Molecular Target Therapy of Cancer

Selected Publications

  • Selective Purification and Chemical Labeling of Target Protein on Ruthenium Photocatalyst- Immobilized Affinity Beads, M. Tsushima, S. Sato, H. Nakamura, ChemCommun.in press.
  • The Life of Pi Star: Exploring the Exciting and Forbidden Worlds of the Benzophenone Photophore, G. Dormán, H. Nakamura, A. Pulsipher, G. D. Prestwich, Chem. Rev. 116, 1528415398 (2016)
  • Total Synthesis of Feglymycin based on a Linear/Convergent Hybrid Approach using Micro-flow Amide Bond Formation.S. Fuse, Y. Mifune, H. Nakamura, H. Tanaka, Nature Commun. 7, 13491 (2016)
  • Generation of 4-Isoxazolyl Anion Species: Facile Access to Multifunctionalized Isoxazoles, T. Morita, S. Fuse, H. Nakamura, Angew. Chem. Int. Ed. 55, 13580-13584 (2016)
  • Synthesis of 2-Indolyltetrahydroquinolines via Zinc(II)-Catalyzed Intramolecular Hydroarylation- Redox Cross-Dehydrogenative Coupling of N-Propargylanilines with Indoles, G. Li and H. Nakamura, Angew. Chem. Int. Ed. 55, 6758-6761 (2016)